Ten Weird Side Effects Zoloft Gave Me | The Odyssey Online
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Ten Unexpected Zoloft Side Effects I Experienced in the First Three Months

I started a low dose of Sertraline, a generic form of the selective serotonin reuptake inhibitor (SSRI) in January of 2018 in order to control my derealization, anxiety, and OCD. Here are some of the weirdest side effects I wasn't told to expect.

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Ten Unexpected Zoloft Side Effects I Experienced in the First Three Months
Photo by Ava O'Malley

In This Article:

Muscle twitches and tremors.

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One night after being on Zoloft for about two weeks, I felt unable to control the sudden burst of activity in my right quad. My leg was twitching and jerking like crazy, and it lasted for a few days. I also had a flare up of eye twitching and calf spasms, but those went away pretty quickly.

No more tears.

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Before Zoloft, I was a huge cry baby. Within the first month, I realized that I physically could not cry. I tried everything to invoke tears- sad movies, emotional fan fiction, even Adele's discography. Nothing could inspire anything more than a meager mist to gather in my eyes. I couldn't cry like a regular person until the fifth or sixth month of taking Zoloft.

Impaired vision.

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My significant other and I had actually started Zoloft around the same time by coincidence, so it was nice to have a sounding board for all of my weird side effects. He and I both noticed that our vision had taken a turn for the worse over the course of the first two weeks. I found myself having to squint even with my glasses on, especially at things in the distance. This went away after about a month.

Worsened anxiety.

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I was extremely on edge the first two weeks I began the drug. I think I was over analyzing every single side effect and letting it freak me out. I felt like I could feel the chemicals in my brain swishing around, rearranging the wiring in there. One morning, I woke up after a particularly colorful dream, and felt far too much brain activity going on for six am. I ended up suffering a full blown panic attack, possibly one of the worst ones to date, that morning. After the first three weeks, however, my anxiety slowly faded away.

Wild dreams.

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My dreams went from simple, sometimes strange, but pretty average scenes to absolutely ridiculous, colorful, and frightenly realistic episodes. I would look forward to going to sleep every night to see what kind of show my brain would put on that evening.

No sex drive.

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This one was a huge bummer for me, and something that my sweet, sixty-something year old psychiatrist probably felt too awkward to talk to me about. Before Zoloft, I had a very high sex drive. After, I was basically a nun. I noticed my libido decrease probably after two months on the drug, and didn't get it back for about six whole months. I wasn't repulsed by the idea of sex, nor did I avoid it, but it just didn't occupy as prominent a space in my mind anymore. I'm glad that my partner and I were both on Zoloft, because we were both temporarily neutered together.

No orgasms, either.

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This goes hand in hand with #6. Not only was I less interested in having sex, but I couldn't feel sexual pleasure in the same way either. After two or three months on Zoloft, I realized, "Hey, my orgasms kind of suck." What used to be a fireworks display was now a singular birthday candle getting blown out. This made me even less interested in sex, because it just didn't feel good anymore. Thankfully, I got my orgasms back after six or seven months. Both decreased libido and sexual sensation are common side effects of Zoloft, I discovered after some internet exploring.

Major brain fog.

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The first two weeks of starting Zoloft were the hardest. My brain was going through a lot of changes, and I just couldn't think like I used to. I would zone out in class, forget my sentence halfway through, and take forever to remember events that occurred mere hours ago. I had to ask a few teachers to let me retake tests after the fog cleared, because my grades took a slight dip during the first two weeks. It all cleared up before week four, though.

Constant urge to sneeze.

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This was probably my weirdest side effect. I felt like I needed to sneeze all the time, but I just couldn't. Hey, maybe it goes along with the orgasm thing. I would try everything to prompt a sneeze- staring into bright slights, blowing my nose, smelling spicy scents, and still, nothing. My psychiatrist wasn't completely sure if this was a direct side effect of the medication, but I'm a firm believer that it was.

Slow and steady relief.

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My anxiety, derealization, and OCD symptoms didn't just disappear overnight. It was so gradual, I didn't even realize it. One day, I suddenly realized that I had been living without anxiety for weeks, and that the change was so gradual I had never even noticed.

Although these symptoms seem a bit scary, my life has improved drastically since starting my SSRI. It's definitely a serious decision that requires a lot of planning and consideration, but if you're struggling with a mental illness, I would suggest reaching out to a psychiatrist.

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This article has not been reviewed by Odyssey HQ and solely reflects the ideas and opinions of the creator.
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