You have an apartment, you have a routine, and you have certain expectations on how life should be. This can cause quite a shock when you decide to go back home for an extended period of time. Things are shifted around, the layout is sort of familiar but different at the same time, and your bed doesn't feel like your own.
It's almost like entering the Twilight Zone.
For the first week or so you are kind of lost. Most of the time you don't have the option of continuing your normal routine, so it can take a while for you to figure out a new one that works for you. It's easy to fall into the trap of sleeping all day when you a fresh from a particularly exhausting semester. Of course, this just makes you feel more exhausted because your body isn't used to not doing anything. Believe it or not, your body will feel less exhausted the more you get out and do stuff. If you just lay in bed watching Netflix all day, your body will continue to feel worse and worse until you finally decide to do stuff.
When you first start to be more active, it is possible that you will feel exponentially worse, but that's mainly because your body has become more used to being completely inactive than to being active. This buffering time depends on how long you allowed yourself to just lay around.
After you become more active, you begin to become more settled. You find a partial schedule that works for the time being, and everything seems to be a lot more familiar. It's not that anything was inherently different, to begin with, but your brain needed time to readjust to this environment.
Finally, you are able to get back into the swing of things. Your brain is able to fully process that this is your home, and you can fully relax. A major part of the problem is feeling like a guest when you come back from a long stint at university. You realize that all your worrying has been for not and that there truly is no place like home.